俞琼教授-凯时尊龙官网

 俞琼教授-凯时尊龙官网

博士生导师

俞琼教授


基本情况

姓名:

俞琼

                      

性别:

职称:

教授

所在部门:

流行病与卫生统计

最后学历:

研究生

最高学位:

博士

电话:

85619451

email



详细情况

所在学科专业:

流行病与卫生统计学

研究方向:

分子流行病学,基因组流行病学,精神卫生流行病学,肿瘤流行病学

讲授课程:

流行病学,循证医学,预防医学,临床流行病学,流行病学原理与方法,流行病学新进展,epidemiologyclinical epidemiology,  

教育经历:

1997.09-2002.06 吉林大学预防医学系本科
  2002.09-2004.09
吉林大学公共卫生学院流行病与卫生统计学硕士
  2004.09-2007.06
吉林大学公共卫生学院医学基因组学博士
  2009.11-2013.05
吉林大学东北亚研究院博士后

工作经历:

2005.09-2007.06    吉林大学公共卫生学院助教
  2007.07-2013.08  
吉林大学公共卫生学院讲师
  2010.02-2011.02  
荷兰乌德勒支大学医学研究中心访问学者
  2013.09-2018.08  
吉林大学公共卫生学院副教授,硕士生导师
  2015.02-2015.12  
美国佐治亚大学访问学者

2018.09-至今 吉林大学公共卫生学院教授,博士生导师

科研项目:

1.国家自然科学基金面上项目:基于microrna技术的精神分裂症相关生物标记物的遗传流行病学研究,2017-202060万,负责人
  2.
国家自然科学基金青年基金:精神分裂症疾病相关标识蛋白与相关候选基因的遗传流行病学研究,2010-201219万,负责人

3.吉林省教育厅科学技术研究规划项目:精神分裂症诊断相关lncrna标志物研究,2019-2020,负责人
  4.
吉林省卫生计生青年科研课题:调控激肽原l蛋白的mirna基因多态性与精神分裂症的关联研究,2015-2016,负责人
  5.
中荷国际合作项目:中荷饥荒年代出生精神分裂症dna甲基化相关位点研究,2016-2017,负责人
  6. 2015
白求恩计划b项目:精神分裂症microrna   的生物标志物研究,2015-201830万,负责人
    7.
白求恩医学部医学科研支持计划青年科研基金项目:调控纤维蛋白肽a蛋白的mirna基因及其靶基因多态性与精神分裂症的关联研究,2014-20155万,负责人
    8.
吉林大学基本科研业务费项目:胎儿期营养不良与精神分裂症pla2g4c基因和pla2g12a基因dna甲基化关系的研究,2010-20115万,负责人
    9.
吉林大学种子基金:精神分裂症相关microrna的遗传流行病学研究,2015-2016,负责人

10. 横向课题:生物医学数据智能分析软件开发,2019-2021,负责人
    11.
儿童超重和肥胖的影响因素及干预研究,2016-2019, 负责人
    12.
吉林大学白求恩医学部教改项目:基于卓越医生培养计划的循证医学课程体系改革研究和实践及案例库建设,2014-2016,负责人
    13.
国家自然科学基金青年基金:基于本体的我国心血管类药物不良反应通路预测方法研究,2017-2019,第二
    14.
国家科技支撑计划项目子项:中国成人精神疾病流行病学调查和疾病负担研究,2012-2014,第三
    15.
卫生部卫生行业科研专项子项:吉林省精神障碍疾病负担及卫生资源利用研究,2012-2014,第三
    16.
国家“十一五”科技支撑计划子课题:高血压、脑卒中常见心理问题现场流行病学调查,2010-2012,第三
    17.
国家自然科学基金面上项目:磷脂酶a2基因家族dna甲基化与精神分裂症关系的表观遗传流行病学研究,2010-2012,第四
    18.
国家自然科学基金面上项目:基因组中雌激素受体β与foxa1dna结合位点解析及其对下游基因的调控作用,2009-2011,第四
    19.
国家自然科学基金面上项目:磷脂酶a2与精神分裂症的关系,2007-2009,第四
    20.
国家“十五”科技攻关子项:食品中有害微生物及生物毒素限量研究与标准,2005-2006,第二
    21.
吉林省科技发展计划项目:羟基脂肪酸类雌激素受体调节物对阿尔兹海默病作用机制研究,2015-2017,第三
    22.
吉林省卫生厅、科技厅重点科研课题:吉林省区域慢性病疾病谱现状流行病学调查,2010-2013
    23.
中国-荷兰国际科研合作项目:长春市儿童孤独症筛查研究,2010-2013,第四

学术论文:

1. mengdi jin, xiaojing zhu,   yaoyao sun, zhijun li, xinwei li, lizhe ai, yang he,   yane liu, ningning jia, guoyan hu, xingyao cui,   mengtong xie, yuqing yang, qiong yu*. identifcation   of peripheral blood mirna biomarkers in first‑episode drug‑free   schizophrenia patients using bioinformatics strategy. molecular neurobiology,   2022, 59(8):4730-4746. (通讯作者)

2. mengtong xie, zhijun li,   xinwei li, lizhe ai, mengdi jin, ningning jia, yuqing yang, weizhen li,   fengyu xue, min zhang, qiong yu*. identifying crucial biomarkers in   peripheral blood of schizophrenia and screening therapeutic agents by   comprehensive bioinformatics analysis. journal of psychiatric research. 2022152:86-96. (通讯作者)

3. zhijun li , xinwei li ,   mengdi jin , yang liu , yang he , ningning jia , xingyao cui , yane liu ,   guoyan hu , qiong yu*. identification of potential biomarkers and their   correlation with immune infiltration cells in schizophrenia using combinative   bioinformatics strategy. psychiatry research, 2022, 314 : 114658. (通讯作者)

4. yane liu, duo wang,   zhijun li, xinwei li, mengdi jin, ningning jia, xingyao cui, guoyan hu,   tongyutang*, qiong yu*. pan‑cancer analysis on the role of pik3r1 and pik3r2   in human tumors. scientifc reports. 2022, 12: 5924. (共同通讯作者)

5. zhijun li, xinwei li,   mengdi jin, yang liu, yang he, ningning jia, xingyao cui, yane liu, guoyan   hu, qiong yu*. identification of potential blood biomarkers for early   diagnosis of schizophrenia through rna sequencing analysis. journal of   psychiatric research, 2022,147: 39-49. (通讯作者)

6. li xw, zhang my, li zj, ai lz, jin md, jia nn, xie   mt, yang yq, li wz, dong l, yu q*. world j   psychiatry. 2022, 12(7):904-914. (通讯作者)

7. 刘洋,吕跃斌,吴兵,魏源,陈晨,周锦辉,赵峰,李昕蔚,王君,李峥,李成橙,吉赛赛,李亚伟,郭彦波,鞠爱鹏,薛锴,施小明*,俞琼*. 中国9个长寿地区老年人尿砷水平与贫血的关联. 中华医学杂志, 2022,102(2): 101-107.(共同通讯作者)

8. x. cui#, s. wang#, n. jiang#, z. li, m. jin, b.   yang, n. jia, g. hu, y. liu, y. he, y. liu, s. zhao, q. yu*. establishment of   prediction models for covid-19 patients in different age groups based on   random forest algorithm. qjm : an international journal of medicine,   2021, 1-7. (通讯作者)

9.#, #, , , , , , , , , , , *, *. a retrospective study of 268 patients with sars-cov-2 infection to   evaluate the association between blood glucose and severity of covid-19   pneumonia and patient mortality. med sci monit. 2021, 27:e932156.(共同通讯作者)

10. zhijun li#, nan jiang#, xinwei li, bo yang ,   mengdi jin , yaoyao sun , yang he , yang liu , yueying wang , daoyuan si ,   piyong ma , jinnan zhang , tianji liu* , qiong yu*. two novel nomograms based   on inflammatory cytokines or lymphocyte subsets to differentially diagnose   severe or critical and non-severe covid-19. aging (albany ny). 2021,   13(14):17961-17977.(共同通讯作者)

11. yang liu, bin liu, yang   he, zhijun li, xinwei li, duo wang, zongqiang wang , ying xu, qiong yu*.   analysis of risk factors related to breast cancer metastasis: a retrospective   nested case-control study. jbuon, 2021, 26(4): 1415-1421(通讯作者)

12. yang liu, bin liu, yang he, zhijun li, xinwei   li, duo wang, zongqiangwang, ying xu, qiong yu*. analysis of risk factors   related to breast cancer metastasis: a retrospective nested case-control   study. jbuon, 2021, 26(4): 1415-1421(通讯作者)

13. jiang n#, li z#, yang b, jin m, sun y, he y, liu   y, wang y, si d, ma p, zhang j, liu t*, yu q*. peripheral inflammatory   cytokines and lymphocyte subset features of deceased covid-19 patients.   biomed res int. 2021, 2021:9101082.(共同通讯作者)

14. nan jiang#, yaoyao sun#,   hongyan sun#, bo yang, juan tan, huan sun, shuai wang, qiong yu*. the   positive rate of igm and igg antibodies against sars-cov-2 is similar in severe   and non-severe covid-19 patients. revista romana de medicina de laborator.   2021, 29(1):85-91. (通讯作者)

15.mengdi jin, zhijun li,   yaoyao sun, mingyuan zhang, xin chen, hongguang zhao*, qiong yu*. association   analysis between the interaction of ras family genes mutations and papillary   thyroid carcinoma in the han chinese population. international journal of   medical sciences. 2021; 18(2): 441-447.(共同通讯作者)

16. 张茗媛, 吕跃斌, 周锦辉, 赵峰, 陈晨, 谭启跃, 曲英莉, 吉赛赛, 路凤, 刘迎春, 顾珩, 吴兵, 曹兆进, 俞琼*, 施小明*. 中国 9 个长寿地区 65 岁及以上人群血铅浓度与认知功能受损的关联研究. 中华预防医学杂志, 2021, 55 (1): 66-71. (共同通讯作者)

17.rixin li, bin liu, yumei   liu, yang liu, yang he, duo wang, yunxiang sun, ying xu, qiong yu*. elevated   serum lipid level can serve as early signal for metastasis for non-small cell   lung cancer patients: a retrospective nested case-control study. journal of   cancer, 2020, 11(23): 7023-7031.(通讯作者)

18. yaoyao sun, wei geng,   yang he, zhijun li, mengdi jin, yang liu, qiong yu*. survey of mental health   effects among health care workers involved with the covid-19 outbreak.   iranian journal of public health, 2020, 49(11):2214-2216.(通讯作者)

19. mingyuan zhang, zhijun   li, shuman yang, yaoyao sun, mengdi jin, xin chen, qiong yu*. the association   between dietary patterns and depressive symptoms in chinese adults. biomed research   international, 2020, 2020:8380151.(通讯作者)

20. yaoyao sun, yueying   wang, rixin li, guojun kang, mingyuan zhang, xin chen, mengdi jin, yang liu,   yang he, xiaojing zhu, qi kang, fengfeng zhou, qiong yu*. surgical resection   of primary tumor is associated with prolonged survival in low-grade   pancreatic neuroendocrine tumors. clinics and research in hepatology and   gastroenterology. 2021,45(1):101432.(通讯作者)

21 .fu y, zhou n, bai w, sun   y, chen x, wang y, zhang m, kou c, yu y, yu q*. association of the cacna2d2   gene with schizophrenia in chinese han population. peerj. 2020, 8:e8521.(通讯作者)

22. mingjia yang, zhijun li,   mengdi jin, yaoyao sun, yang he, yang liu, qiong yu*. associations between   three microrna gene polymorphisms and schizophrenia susceptibility in a han   chinese population. asian journal of psychiatry, 2020, 50: 102035.(通讯作者)

23. xin feng, xubing hao,   ruoyao shi, zhiqiang xia, lan huang, qiong yu*, fengfeng zhou*. detection and   comparative analysis of methylomic biomarkers of rheumatoid arthritis.   frontiers in genetics. 2020, 11: 238.(共同通讯作者)

24. guojun kang, qi kang,   xiaojing zhu, rixin li, shangchao zhang, yaoyao sun, mingyuan zhang, xin   chen, yueying wang, huiyi jiang, yaqin yu, qiong yu*. association between   hla-b polymorphisms and autism spectrum disorder in chinese population. iran   j pediatr, 2020, 30(1):e90110.(通讯作者)

25. 康琪, 吕跃斌, 魏源, 石婉荧, 段俊, 周锦辉, 王蛟男, 赵峰, 曲英莉, 刘玲,刘迎春, 曹兆进, 俞琼*, 施小明*. 中国8个长寿地区65岁及以上老年人抑郁症状影响因素分析. 中华流行病学杂志, 2020, 41(1):20-24. (共同通讯作者)

26. yingli fu, na   zhou, yaqin yu, huiping zhang, yaoyao sun, mingyuan zhang, xin chen, yueying   wang, qiong yu*. profiling of schizophrenia-associated serum peptides by   maldi-tof-ms. journal of neural transmission(vienna). 2020, 127(1):95-101.(通讯作者)

27. sun y, kang g, zhu x, li   r, kang q, zhang m, wang y, chen x, yu y, yu q*. association of mad1l1 polymorphism   (rs871925) with prenatal famine exposure and schizophrenia in a chinese   population: a case-control study. iubmb life. 2020, 72(2):259-265.(通讯作者)

28. mingjia yang, na zhou, huiping zhang, guojun   kang, bonan cao, qi kang, rixin li, xiaojing zhu, wenwang rao, qiong yu*.   kininogen-1 as a protein biomarker for schizophrenia through mass   spectrometry and genetic association analyses. peerj, 2019,   7 :e7327. (通讯作者)

29. guojun kang,   shangchao zhang, yaqin yu, qiong yu*. association of granzyme b gene polymorphism   with autism spectrum disorder in northeast han chinese population. iran red   crescent med j. 2019, 21(9): e92422. (通讯作者)

30. guojun kang#, yanchi   zhang#, rui liu, rixin li, qi kang, xiaojing zhu, lijuan yan, yaqin yu, qiong   yu*. fibrinogen and kininogen are potential serum   protein biomarkers for depressive disorder. clinical laboratory, 2019, 65(10):1887-1893.(通讯作者)

31. xiaojing zhu, rixin li,   guojun kang, qi kang, wenwang rao, mingjia yang, bonan cao, mingyuan zhang,   yaoyao sun, yueying wang, xin chen, yaqin yu, and qiong yu*. cacna1c   polymorphism (rs2283291) is associated with schizophrenia in chinese males: a   case-control study. disease markers, 2019. 2019:8062397.(通讯作者)

32.rao wenwang, yang   mingjia, cao bonan, you yueyue, zhang yangyu, liu yingyu, kou changgui, yu   yaqin, mcassidy ryan, yu qiong, zhang xiangyang. psychological distress in   cancer patients in a large chinese cross-sectional study. journal of   affective disorders. 2019, 245:950-956.(共同通讯作者)

33. shangchao zhang, na   zhou, rui liu, wenwang rao, mingjia yang, bonan cao, guojun kang, qi kang,   xiaojing zhu, rixin li, yaqin yu, qiong yu*. association between   polymorphisms of the complement 3 gene and schizophrenia in a han chinese   population. cell physiol biochem, 2018, 466:2480-2486.(通讯作者)

34.kang q, kang g, li r, zhu   x, yu y, yu q. relationship of gallbladder diseases with sociodemographic   characteristics, lifestyle, and chronic diseases in northeastern   china. int. j. environ. res. public health2018, 15(11)2596. (通讯作者)

35rui liu, lingfeng ning,   xiaoli liu, huiping   zhang, yaqin yu, shangchao zhang, wenwang rao,   jieping shi, hui sun, qiong   yu. association between single nucleotide   variants of vascular endothelial   growth factor a and the risk of   thyroid carcinoma and nodular goiter in a han   chinese population.   oncotarget, 2017, 8(9):15838-15845.(通讯作者)
  36. wenwang rao, na zhou, huiping zhang, rui liu, shangchao zhang, yingying     su, guang yang, yue ma, jieping shi, yaqin yu, qiong yu*. a   case-control   study of the association between polymorphisms in the   fibrinogen alpha chain   gene and schizophrenia. disease markers. 2017,   2017: 3104180,
(通讯作者)
   37. wenwang rao, xiangdong du, yingyang zhang, qiong yu*, li hui, yaqin   yu, changgui kou, guangzhong yin, xiaomin zhu, lijuan man, jair c. soares,   xiang yang zhang. association between forkhead-box p2 gene polymorphism and     clinical symptoms in chronic schizophrenia in a chinese population. j   neural   transm. 2017 apr 18.
(共同通讯作者)
  38.qiong yu, bo pang, rui liu, wenwang rao, shangchao zhang, yaqin yu.      appropriate body mass index and waist-hip ratio cutoff points for     overweight and obesity in adults of northeast china. iran j public   health,   2017, 46,
8):1038-1045.
  39.mingjia yang, yaqin yu, qiong yu*. the association between diet and mental     health in chinese people, iran red crescent med j. 2017, 19(8):e59534.  
(通讯作者)
  40. ning lifeng, rao wenwang, yaqin yu, xiaoli liu, yuchen pan, yuan ma, rui     liu, shangchao zhang, hui sun, qiong yu*. association between the kras   gene   polymorphisms and papillary thyroid carcinoma in a chinese han   population.   journal of cancer. 2016,7(15): 2420-2426.
(通讯作者)
  41. wenwang rao, yingying su, guang yang, yue ma, rui liu, shangchao zhang,   shibin wang, yingli fu, changgui kou, yaqin yu, qiong yu*. cross-sectional     associations between body mass index and hyperlipidemia among adults   in   northeastern china. international journal of environmental research   and   public health. 2016, may 20;13(5).(
通讯作者)
  42. xin liu, shuang li, xuejun lin, kangkang yan, longyu zhao, qiong yu*,     xiaodong liu*. axin2 is associated with papillary thyroid carcinoma.   iran red   crescent med j, 2016, 18(2):e20960.
(共同通讯作者)
  43. ning l, yu y, liu x, ai l, zhang x, rao w, shi j, sun h, yu q*.   association analysis of met gene polymorphism with papillary thyroid     carcinoma in a chinese population. int j endocrinol. 2015, 2015:405217.
(通讯作者)
  44. l.f. ning, y.q. yu, e.t. guoji, c.g. kou, y.h. wu, j.p. shi, l.z. ai, q.     yu*. meta-analysis of differentially expressed genes in autism based   on gene   expression data. genetics and molecular research. 2015, 14   (1): 2146 – 2155.
(通讯作者)

45. ai l, yu y, liu x, wang c, shi j, sun h, yu q*.   are the snps of nkx2-1   associated with papillary thyroid carcinoma in   the han population of northern   china? front med201481):113-117.(通讯作者)
   46. zhou n, wang j, yu y, shi j, li x, xu b, yu q*. mass spectrum   analysis of   serum biomarker proteins from patients with schizophrenia.   biomedical   chromatography
201428:   654-659. (通讯作者)
   47.
俞琼, 张瑞明, 姜媛, 王猛, 于雅琴, 史杰萍. taar6基因多态性与精神分裂症关联性的meta分析. 吉林大学学报(医学版), 2014, 40 (3): 633-640.
   48. lizhe ai, xiaoli liu, yuhang yao, yaqin yu, hui sun, qiong yu*.     associations between rs965513/rs944289 and papillary thyroid carcinoma   risk:   a meta-analysis. endocrine, 2014, 47: 428-434.
(通讯作者)
   49.
刘欣, 李双, 林雪君, 颜康康, 赵龙宇, 鲍红红, 俞琼*, 刘晓冬*. itga3tp53inp2axin2基因多态性与甲状腺乳头状癌的关联性分析. 吉林大学学报(医学版), 2014, 40(2): 381-386. (共同通讯作者)
   50. zhou n *, yu q *, li x, yu y, kou c, li w, xu h, luo x, zuo l,   kosten tr, zhang xy. association of the dopamine b-hydroxylase 19 bp   insertion/deletion   polymorphism with positive symptoms but not tardive   dyskinesia in   schizophrenia. human psychopharmacology, 2013, 28(3):   230-237. (
共同第一作者)
  51. li w*, zhou n*, yu q*, li x, yu y, sun s, kou c, chen dc, xiu mh, kosten     tr, zhang xy. association of bdnf gene polymorphisms with   schizophrenia and   clinical symptoms in a chinese population. am j med   genet b neuropsychiatr   genet, 2013, 162b(6):538–545. (*
共同第一作者)
  52. yu q, yu y, shi j, sang h. association between pnpla8 gene polymorphism     and schizophrenia in male patients. s afr j psych, 2013, 19(3):86-87.
(第一作者)
  53.
俞琼,付颖利,冯佳,史杰萍,于雅琴. 5-羟色胺1a受体基因多态性与精神分裂症关联性的meta分析. 吉林大学学报(医学版),2011374):678-681.
  54. yu q
meng x shi jyu y. genetic association between the polymorphism of cytosolic     pla2 gene family and schizophrenia. front med china20104(1)101-105.(第一作者)

55. 俞琼,付颖利,冯佳,谢冰,寇长贵,于雅琴. 5-羟色胺1a受体基因多态性与自杀关联性的meta分析. 吉林大学学报(医学版),2010366): 1134-1138.
   

著作教材:

1.《社区卫生学》,2011,科学技术出版社
  2.
《全国乡镇(社区)医护人员培训试用教材》丛书预防医学分册,2010
  3.
《函授本科试用教材》预防医学分册,2010
  4.
《预防医学》教育部高等教育课程改革和建设规划教材,2012
  5.
《公卫医师综合应试指导》,2014,中国协和医科大学出版社
  6.
《公卫医师实践技能应试指导》,2014,中国协和医科大学出版社
  7.
《流行病学大参考书》第三卷,2014,人民卫生出版社
  8.
全国高等学校卫生检验与检疫专业《免疫学检验》第二版,2015,人民卫生出版社
  9.
“金色年华”系列读本《老年健康与保健读本》,2017

10.预防医学留学生英文教材,2019,浙江大学出版社

获奖情况:

1.吉林大学优秀博士毕业研究生,2007
  2.
吉林大学公共卫生学院第四届中青年教师讲课比赛一等奖,2007
  3.
吉林大学第三届青年教师教学大赛三等奖,2008
  4.
吉林大学公共卫生学院科技创新优秀党员,2011
  5.
吉林省公共卫生科学技术奖三等奖,2014

6. 吉林省科学技术成果奖二等奖,2017

7. 国家人口与健康科学数据共享服务平台“共享杯”大学生科技资源共享服务创新大赛--优秀指导教师,2018

8. 吉林大学第八届青年教师教学大赛三等奖,医学部二等奖,2018

9. 国家人口与健康科学数据共享服务平台“共享杯”大学生科技资源共享服务创新大赛--突出贡献奖,2019

10. 吉林大学公共卫生学院第一届研究生教师讲课比赛第二名,2019

社会兼职:

中国抗癌协会肿瘤流行病学专业委员会第二届青年委员会委员

中华预防医学会老年病预防与控制专委会第二届委员会委员

中华预防医学会伤害预防与控制分会青年委员会第一届委员
 
吉林省人兽共患病学会第二届理事
 
国家自然科学基金项目同行评审专家
 
长春市医学会第十二届理事会心身医学专科委员会委员

吉林大学附属第一医院伦理委员会委员

吉林大学附属第一医院干细胞临床研究科学委员会委员

吉林大学附属口腔医院伦理委员会委员


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